The reemergence of whooping cough in the 21st century. Literature review and update
DOI:
https://doi.org/10.56294/sctconf2023475Keywords:
Pertussis, Whooping Cough, Bordetella Pertussis, Pertussis Vaccine, Bordetella Virulence FactorsAbstract
Whooping cough (pertussis) caused by Bordetella pertussis is a highly contagious respiratory tract infection. continues to be a global public health problem. The World Health Organization reported 151,074 cases of pertussis worldwide and estimated 89 000 deaths in 2018. In recent years, pertussis epidemics have been observed in countries that have maintained high vaccination coverage. According to the official report of the Ministry of Health and Sports, the total accumulated cases of Coqueluche in Bolivia reach 756, of which 469 are up to 5 years old and 287 older than that age range and 8 deaths had to be regretted until August 10, 2023. Coqueluche is a notifiable disease. It is important to reflect that infectious diseases have no borders; a relevant question would be whether Bolivia is prepared or is failing to control this outbreak of reemerging disease, after COVID-19. We should not lower our guard or dismiss early action; new preventive strategies are needed.
References
1. Centers for Disease Control and Prevention (CDC). Epidemiology and Prevention of Vaccine-Preventable Diseases. Pertussis. 2021. [Internet]. Available at: https://www.cdc.gov/vaccines/pubs/pinkbook/pert.html
2. Falleiros Arlant, Luiza Helena et al. Pertussis in Latin America: epidemiology and control strategies. Expert review of anti-infective therapy. [Internet]. vol. 12,10 (2014): 1265-75. Available at: https://doi.org/10.1586/14787210.2014.948846
3. Edwards K M, Decker M D. Pertussis vaccines. In: Plotkin S A, Orenstein W A, Offit P A, eds. Plotkin’s Vaccines. 7 ed. Elsevier; 2018: Cap. 44. pages 711-761
4. World Health Organization. Pertussis vaccines: World Health Organization position paper, August 2015-Recommendations. Vaccine. [Internet]. 2016; 34 (12): 1423-5. Available at: https://doi.org/10.1016/j.vaccine.2015.10.136
5. World Health Organization. Pertussis. 2023. [Internet] . Available at: https://www.who.int/health-topics/pertussis#tab=tab_2
6. Vaccine Information. Whooping cough (Pertussis). Vaccine-Preventable Diseases. [Internet]. Available at: https://vaccineinformation.org/whooping-cough/
7. Skoff, Tami H et al. The Epidemiology of Nationally Reported Pertussis in the United States, 2000-2016. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [Internet]. vol. 68,10 (2019): 1634-1640. Available at: https://doi.org/10.1093/cid/ciy757
8. World Health Organization. Health topics-Pertussis. (2023). Available at: https://www.who.int/health-topics/pertussis#tab=tab_1
9. Moraga-Llop FA, Campins-Martí M. Nuevas perspectivas de la tos ferina en el siglo XXI. ¿Estamos fracasando en su control? Enferm Infecc Microbiol Clin.2011;29:561–3. Disponible en: DOI: 10.1016/j.eimc.2011.07.009
10. Centers for Disease Control and Prevention (CDC). “Vaccine preventable deaths and the Global Immunization Vision and Strategy, 2006-2015.” MMWR. Morbidity and mortality weekly report vol. 55,18 (2006): 511-5. https://pubmed.ncbi.nlm.nih.gov/16691182/
11. Jackson DW, Rohani P. Perplexities of pertussis: Recent global epidemiological trends and their potential causes. Epidemiol Infect. 2013;16:1–13. https://doi.org/10.1017/s0950268812003093
12. Centers for Disease Control and Prevention. Pertussis epidemic. Whashington, 2012. MMWR Morb Mortal Wkly Rep. 2012;61:517–22. https://pubmed.ncbi.nlm.nih.gov/22810264/
13. Australian Institute of Health and Welfare (AIHW). Whooping cough in Australia. 2023. [Internet]. Available at: https://www.aihw.gov.au/getmedia/303c1ab7-9b04-4544-9c5d-852c533ac87a/aihw-phe-236_WhoopingCough.pdf.aspx
14. Ministerio de Salud y Deportes de Bolivia. Vacunación en Bolivia llega a 16.030.962 dosis aplicadas, casos positivos covid de hoy 42 y acumulado de tosferina 779. [Internet]. Disponible en: Ministerio de Salud y Deportes de Bolivia - VACUNACIÓN EN BOLIVIA LLEGA A 16.030.962 DOSIS APLICADAS, CASOS POSITIVOS COVID DE HOY 42 Y ACUMULADO DE TOSFERINA 779 (minsalud.gob.bo)
15. Havers Fiona P., Moro Pedro L. et al. Pertussis. In: Centers for Disease Control and Prevention. Epidemiology and Prevention of Vaccine-Preventable Diseases. [Internet].14th ed. Washington, D.C. Public Health Foundation; 2021. p. 239 - 254. Available at: https://www.cdc.gov/vaccines/pubs/pinkbook/pert.html
16. Warfel, Jason M et al. Airborne transmission of Bordetella pertussis. The Journal of infectious diseases. [Internet]. vol. 206,6 (2012): 902-6. Available at: https://doi.org/10.1093/infdis/jis443
17. Centers for Disease Control and Prevention. Pertussis. En: Atkinson W, Hamborsky J, McIntyre L, Wolfe S, eds. Epidemiology and prevention of vaccine-preventable diseases, 8th ed. Washington D.C.: Public Health Foundation; 2005:75–88.
18. Cherry, James D. The epidemiology of pertussis: a comparison of the epidemiology of the disease pertussis with the epidemiology of Bordetella pertussis infection. Pediatrics. [Internet]. vol. 115,5 (2005): 1422-7. Available at: https://doi.org/10.1542/peds.2004-2648
19. Centers for Disease Control and Prevention. Pertussis (Whooping Cough). For Healthcare Professionals. [Internet]. Available at: http://www.cdc.gov/pertussis/materials/hcp.html
20. Nelson, J D. The changing epidemiology of pertussis in young infants. The role of adults as reservoirs of infection. American journal of diseases of children (1960). [Internet]. vol. 132,4 (1978): 371-3. Available at: https://doi.org/10.1001/archpedi.1978.02120290043006
21. Folaranmi, Temitope et al. Systematic review and meta-analysis of pertussis epidemiology in Latin America and the Caribbean: 1980-2015. Revista panamericana de salud publica = Pan American journal of public health. [Internet]. vol. 41 e102. 17 Nov. 2017. Available at: https://doi.org/10.26633/rpsp.2017.102
22. Gentile, Angela et al. Pertussis in Latin America and the Hispanic Caribbean: a systematic review. Expert review of vaccines. [Internet]. vol. 18,8 (2019): 829-845. Available at: https://doi.org/10.1080/14760584.2019.1643241
23. Zenovio Calderon R. Tesis. La coqueluche en nuestro país. Universidad Mayor de San Andres. Facultad de Ciencias Médicas. Internet. (1924) Disponible en: https://repositorio.umsa.bo/xmlui/handle/123456789/15280
24. Dirección General de Epidemiología. Ministerio de Salud y Deportes. Situación epidemiológica de tosferina (coqueluche). 2023 Disponible en: https://www.minsalud.gob.bo/7759-movilizacion-de-brigadas-de-salud-en-santa-cruz-muestra-tendencia-de-disminucion-de-casos-sospechosos-de-tosferina
25. Craig, Rodger et al. Asymptomatic Infection and Transmission of Pertussis in Households: A Systematic Review. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [Internet] vol. 70,1 (2020): 152-161. Available at: https://doi.org/10.1093/cid/ciz531
26. Mattoo, Seema, and James D Cherry. “Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies.” Clinical microbiology reviews vol. 18,2 (2005): 326-82. doi:10.1128/CMR.18.2.326-382.2005. Available at: https://doi.org/10.1128/cmr.18.2.326-382.2005
27. Strebel, P et al. Population-based incidence of pertussis among adolescents and adults, Minnesota, 1995-1996. The Journal of infectious diseases. [Internet]. vol. 183,9 (2001): 1353-9. Available at: https://doi.org/10.1086/319853
28. Gilberg, Serge et al. Evidence of Bordetella pertussis infection in adults presenting with persistent cough in a french area with very high whole-cell vaccine coverage. The Journal of infectious diseases. [Internet]. vol. 186,3 (2002): 415-8. Available at: https://doi.org/10.1086/341511
29. Postels-Multani, S et al. Symptoms and complications of pertussis in adults. Infection. [Internet]. vol. 23,3 (1995): 139-42. Available at: https://doi.org/10.1007/bf01793853
30. Schmitt-Grohé, S et al. Pertussis in German adults. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [Internet]. vol. 21,4 (1995): 860-6. Available at: https://doi.org/10.1093/clinids/21.4.860
31. De Serres, G et al. Morbidity of pertussis in adolescents and adults. The Journal of infectious diseases. [Internet]. vol. 182,1 (2000): 174-9. Available at: https://doi.org/10.1086/315648
32. Mertens, P L et al. An epidemic of pertussis among elderly people in a religious institution in The Netherlands. European journal of clinical microbiology & infectious diseases: official publication of the European Society of Clinical Microbiology. [Internet]. vol. 18,4 (1999): 242-7. Available at: https://doi.org/10.1007/s100960050271
33. Senzilet, L D et al. Pertussis is a frequent cause of prolonged cough illness in adults and adolescents. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. [Internet]. vol. 32,12 (2001): 1691-7. Available at: https://doi.org/10.1086/320754
34. Wirsing von König, C H, and H Finger. Role of pertussis toxin in causing symptoms of Bordetella parapertussis infection. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology. [Internet]. vol. 13,6 (1994): 455-8. Available at: https://doi.org/10.1007/bf01974634
35. Trollfors, B, and E Rabo. Whooping cough in adults. British medical journal (Clinical research ed.). [Internet]. vol. 283,6293 (1981): 696-7. Available at: https://doi.org/10.1136/bmj.283.6293.696
36. Heininger, U et al. Clinical findings in Bordetella pertussis infections: results of a prospective multicenter surveillance study. Pediatrics. [Internet]. vol. 100,6 (1997): E10. Available at: https://doi.org/10.1542/peds.100.6.e10
37. Rutledge, Renee K, and Erica C Keen. Images in clinical medicine. Whooping cough in an adult. The New England journal of medicine. [Internet]. vol. 366,25 (2012): e39. Available at: https://doi.org/10.1056/nejmicm1111819
38. Mattoo, Seema, and James D Cherry. Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies. Clinical microbiology reviews. [Internet]. vol. 18,2 (2005): 326-82. Available at: https://doi.org/10.1128/cmr.18.2.326-382.2005
39. Donoso Alejandro, Arriagada Daniela, Cruces Pablo, Díaz Franco. Coqueluche grave: Estado del arte. Rev. chil. infectol. [Internet]. 2012 Jun [cited 2023 Ago 12] ; 29( 3 ): 290-306. Available at: http://dx.doi.org/10.4067/S0716-10182012000300007
40. MS Moya Mir, «La tos ferina en los servicios de urgencias» Emergencias 2003;15:323-325. Disponible en: http://emergencias.portalsemes.org/descargar/los-servicios-de-urgencias-ante-la-tos-ferina/force_download/
41. Organización Panamericana de la Salud. Documentos Tos Ferina (Coqueluche). Alerta Epidemiológica. [Internet] 2012. Available at: https://www.paho.org/es/documentos/16-noviembre-2012-tos-ferina-coqueluche
42. Organización Mundial de la Salud. Vacunas antiferinosas. Documento de posición de la OMS. [Internet]. 2015. Disponible en: https://apps.who.int/iris/bitstream/handle/10665/242416/WER9035-spa.pdf?sequence=49&isAllowed=y
43. WHO. Pertussis vaccines: WHO position paper, August 2015--Recommendations. Vaccine. [Internet]. vol. 34,12 (2016): 1423-5. Available at: https://doi.org/10.1016/j.vaccine.2015.10.136
44. Vygen-Bonnet S, Hellenbrand W, Garbe E, et al. Safety and effectiveness of acellular pertussis vaccination during pregnancy: a systematic review. Infectious Diseases. [Internet]. 2020;20:136. (2020) 20:136. Available at: https://doi.org/10.1186/s12879-020-4824-3
45. D’Heilly C, Switzer C, Macina D. Safety of Maternal Immunization Against Pertussis: A Systematic Review. Infect Dis Ther. [Internet]. 2019;8:543-68. Available at: https://doi.org/10.1007/s40121-019-00265-6.
46. Kilgore, Paul E et al. “Pertussis: Microbiology, Disease, Treatment, and Prevention.” Clinical microbiology reviews vol. 29,3 (2016): 449-86. Available at: https://doi.org/10.1128%2FCMR.00083-15
47. Trollfors, B. Effect of erythromycin and amoxycillin on Bordetella pertussis in the nasopharynx. Infection. [Internet]. vol. 6,5 (1978): 228-30. Available at: https://doi.org/10.1007/bf01642314
48. Hoppe, J E, and A Haug. Treatment and prevention of pertussis by antimicrobial agents (Part II). Infection. [Internet]. vol. 16,3 (1988): 148-52. Available at: https://doi.org/10.1007/bf01644089
49. Tiwari, Tejpratap et al. Recommended antimicrobial agents for the treatment and postexposure prophylaxis of pertussis: 2005 CDC Guidelines. MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports. [Internet]. vol. 54,RR-14 (2005): 1-16. Available at: http://www.jstor.org/stable/24842318.
50. Spicer, Kevin B et al. Occurrence of 3 Bordetella species during an outbreak of cough illness in Ohio: epidemiology, clinical features, laboratory findings and antimicrobial susceptibility. The Pediatric infectious disease journal. [Internet]. vol. 33,7 (2014): e162-7. Available at: https://doi.org/10.1097/inf.0000000000000262
51. Roberts, I et al. Randomized controlled trial of steroids in pertussis. The Pediatric infectious disease journal vol. 11,11 (1992): 982-3.
52. Zoumboulakis, D et al. Steroids in treatment of pertussis. A controlled clinical trial. Archives of disease in childhood. [Internet]. vol. 48,1 (1973): 51-4. Available at: https://doi.org/10.1136/adc.48.1.51
53. Bettiol, Silvana et al. Symptomatic treatment of the cough in whooping cough. The Cochrane database of systematic reviews. [Internet]. 1 CD003257. 20 Jan. 2010, Available at: https://doi.org/10.1002/14651858.cd003257.pub3
54. Krantz, I et al. Salbutamol vs. placebo for treatment of pertussis. Pediatric infectious disease. [Internet]. vol. 4,6 (1985): 638-40. Available at: https://doi.org/10.1097/00006454-198511000-00008
55. Pillay, V, and G Swingler. Symptomatic treatment of the cough in whooping cough. The Cochrane database of systematic reviews. [Internet]. 4 (2003): CD003257. Available at: https://doi.org/10.1002/14651858.cd003257
56. Granström, M et al. Specific immunoglobulin for treatment of whooping cough. Lancet (London, England). [Internet]. vol. 338,8777 (1991): 1230-3. Available at: https://doi.org/10.1016/0140-6736(91)92101-7
57. Halperin, Scott A et al. Is pertussis immune globulin efficacious for the treatment of hospitalized infants with pertussis? No answer yet. The Pediatric infectious disease journal. [Internet]. vol. 26,1 (2007): 79-81. Available at: https://doi.org/10.1097/01.inf.0000247103.01075.cc
58. Danzon, A et al. A double-blind clinical trial on diphenhydramine in pertussis. Acta paediatrica Scandinavica. [Internet]. vol. 77,4 (1988): 614-5. Available at: https://doi.org/10.1111/j.1651-2227.1988.tb10716.x
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Copyright (c) 2023 Jhossmar Cristians Auza-Santiváñez, Ruben Omar Colque-Mollo, Roberto Carlos Jiménez-Fernández, Rommer Alex Ortega Martinez, Antonio Viruez-Soto, Joel Gutiérrez-Beltrán (Author)
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