Microscopic polyangiitis, an onset with diffuse alveolar hemorrhage

Authors

  • Angelo Andy Magallanes Bajaña Centro de salud Santa Lucía. Guayaquil, Ecuador Author
  • Karen Patricia Loaiza Correa Universidad Nacional del Chimborazo. Riobamba, Ecuador Author
  • Alex Daniel Cabezas Euvin Universidad Católica Santiago de Guayaquil. Guayaquil, Ecuador Author
  • Isis Micaela Zambrano Gilces Hospital General Monte Sinaí. Guayaquil, Ecuador Author
  • Evelyn Patricia Navas Vargas Pontificia Universidad Central del Ecuador. Quito, Ecuador Author
  • Mayra Carolina Cortés Morales Universidad Politécnica Estatal de Carchi. Tulcán, Ecuador Author

DOI:

https://doi.org/10.56294/sctconf20241082

Keywords:

Vasculitis, Antineutrophil Cytoplasmic Antibodies, Computed Tomography, Lung Disease

Abstract

Introduction: antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis is a group of complex chronic diseases that cause morbidity, systemic organ damage, therapeutic overload, and risk of relapse. Microscopic polyangiitis (MPA) primarily affects small vessels in the lungs and kidneys, characterized by inflammation that can lead to necrosis of blood vessels, presence of ANCA in the bloodstream, and absence of necrotizing inflammation of the parenchyma in histopathology.

Methods: we present the case of a 58-year-old female patient with hemoptysis, fever, and dyspnea.

Results: laboratory tests show anemia, leukocytosis, positive p-ANCA, hematuria, and proteinuria. The CT scan reveals areas of increased attenuation with a ground-glass pattern and centrilobular nodular opacities occupying the middle lobe and both lower lobes. The patient also tested positive for MPO-ANCA, leading to the diagnosis of ANCA-positive vasculitis, specifically microscopic polyangiitis with pulmonary and renal involvement, pneumonia, and renal insufficiency. She received appropriate medical treatment, resulting in adequate resolution.

Conclusions: microscopic polyangiitis requires interdisciplinary management, which, along with radiological findings, contributes to the early diagnosis and timely treatment of the pathology

References

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Published

2024-07-12

How to Cite

1.
Magallanes Bajaña AA, Loaiza Correa KP, Cabezas Euvin AD, Zambrano Gilces IM, Navas Vargas EP, Cortés Morales MC. Microscopic polyangiitis, an onset with diffuse alveolar hemorrhage. Salud, Ciencia y Tecnología - Serie de Conferencias [Internet]. 2024 Jul. 12 [cited 2025 Feb. 10];3:1082. Available from: https://conferencias.ageditor.ar/index.php/sctconf/article/view/798